Physiology and Genomics of Mastitis

Experimental dissection of host-pathogen interaction in the udder

Participate in the conference:

31st of October – November 2nd, 2011
Evangelische Akademie Tutzing; Germany

Monday, October 31, 2011
until 18:00 Arrival
19:00 Welcome in the castle; Poster mounting & wine
Tuesday, November 1, 2011
08:45 Opening remarks Hans-Martin Seyfert
SESSION 1 Physiology of Mastitis in Ruminants Chair: Holm Zerbe
08:50 Key note Ynte Schukken,
Cornell University, Ithaka, USA
Physiology and patho-physiology of bovine mastitis
09:35 FOR585 /
Wolfram Petzl & Holm Zerbe,
Clinic for Ruminants, LMU Munich, Germany
In vivo models focussing on early host-pathogen-interactions during acute and chronic mastitis
9:55 FOR585 Helmut Blum
Gene Center, LMU Munich, Germany
Escherichia coli infection induces distinct local and systemic transcriptome responses in the mammary gland
10:15 Contributed paper 1 Olga Wellnitz & Rupert Bruckmaier
Veterinary Physiology, Vetsuisse Faculty, University of Bern, Switzerland
Blood constituents in milk during mammary immune response
10:25 Contributed paper 2 David Kerr
University of Vermont, USA
Relationship between bovine dermal fibroblast response to LPS in vitro, and animal response to systemic LPS or E. coli mastitis
10:35 - 11:05 Coffee break
SESSION 2 Cellome of the Mammary Immune Defence Chair: Hans-Joachim Schuberth
11:05 Key note Pascal Rainard
INRA Toulouse, France
Cellular interactions in the mammary gland for the control of infection
11:50 FOR585 /
Juliane Günther & Hans-Martin Seyfert
Leibniz-Institute for Farm Animal Biology, Dummerstorf, Germany
Dissection of pathogen-and cell type specific immune response in the mammary gland: A comparison of Gram-negative vs. -positive bacteria
12:10 Contributed paper 3 Rupert Bruckmaier & Olga Wellnitz
Veterinary Physiology Vetsuisse Faculty, University of Bern, Switzerland
Pathogen specific immune mechanisms in the mammary gland
12:20 Contributed paper 4 Anna Düvel
Institute of Immunology, University of Veterinary Medicine, Hannover, Germany
Distribution of macrophage subtypes in the teat of midlactating and peripartal cows
12:30 Contributed paper 5 Anna Lewandowska-Sabat
Department of Basic Sciences and Aquatic Medicine, The Norwegian School of Veterinary Science, Oslo, Norway
Bovine macrophages and mastitis: in vitro gene response to Staphylococcus aureus exposure
12:40 - 14:00 Lunch
SESSION 3 Mastitis causing Pathogens Chair: Otto Holst
14:00 Key Note Dirk Werling, Royal Veterinary College, London, UK Messing with mastitis – ways to survive and cure
14:45 FOR585 Susanne Engelmann
Institute of Microbiology, Ernst-Moritz-Arndt-University Greifswald, Germany
Physiology and virulence of Staphylococcus aureus mastitis isolates
15:05 FOR585, associated Ulrich Dobrindt
Institut für Hygiene, Westfälische Wilhelms Universität Münster, Münster, Germany
How to define E. coli mastitis isolates - a pathogenomic approach
15:25 Contributed paper 6 Orla Keane
Animal & Bioscience Department, Animal & Grassland Research & Innovation Centre, Teagasc, Ireland
Characterization of Irish mastitis associated bacterial isolates
15:35 - 16:00 Coffe break
SESSION 4 Pathogen perception Chair: Dirk Werling
16:00 Key Note Otto Holst
Research Centre Borstel, Germany
Bacterial PAMPS and their receptors
16:45 FOR585 Katarzyna A. Duda
Research Centre Borstel, Germany
Characterisation of Pathogen-Associated Molecular Patterns isolated from Escherichia coli and Staphylococcus aureus bovine mastitis strains
17:05 Contributed paper 7 Antoni Prenafeta
Department R&D., HIPRA, S.A. Girona, Spain
Efficacy of a Staphylococcus aureus biofilm-embedded bacterin against coagulase-negative staphylococci intramammary infections in dairy cows
17:15 - 18:15 Poster session 2
19:00 Dinner (outside the campus, in the vicinity)
Wednesday, November 2, 2011
SESSION 5 Genetics of Mastitis Susceptibility Chair: Christa Kühn
08:30 Key note Mogens Lund
University of Aarhus, Denmark
Integrative genetics of mastitis
09:15 EADGENE NoE Gilles Foucras
Université de Toulouse, INP, ENVT, Toulouse, France
Current understanding and perspective studies on the mechanisms of susceptibility/resistance to Staphylococcus mastitis using an ovine genetic model.
09:35 M.A.S.-net Bodo Brand & Christa Kühn
Leibniz-Institute for Farm Animal Biology, Dummerstorf, Germany
Expression profiling of E. coli and S. aureus inoculated mammary gland epithelial cells sampled from cows with different genetic predisposition for somatic cell score.
9:55 Contributed paper 8 Johanna Vilkki
MTT Agrifood Research, Finland
Resequencing of cattle QTL regions affecting udder health
10:05 - 10:35 Coffee break
10:35 Contributed paper 9 Regine Preissler
Institute of Agricultural and Nutritional Science, MLU Halle-Wittenberg, Germany
Whole genome association approach to elucidate genetic susceptibility to mastitis in sows
10:45 Contributed paper 10 Hadi Atashi
Department of Animal Science, Faculty of Agriculture, Shiraz University, Iran
BoLA-DRB3 polymorphisms linked to blood mononuclear cell proliferative responses to bovine mastitis pathogen S. aureus
10:55 Contributed paper 11 Nina Schulman
MTT, Agrifood Research Finland, Biotechnology and Food Research, Finland
Confirmation of quantitative trait loci for clinical mastitis in dairy cattle on chromosomes 2, 6, and 20
11:05 Contributed paper 12 Joren Verbeke
Department of Reproduction, Obstetrics, and Herd Health, Faculty of Veterinary Medicine, Ghent University, Belgium
Association of CXCR1 gene polymorphism with apoptosis of blood and milk neutrophils in early lactating dairy heifers
11:15 - 12:00 General discussion and conclusion